—Do you think you will be able to finish your writing by five o’clock today?—. I’ll be bus

问题补充：

—Do you think you will be able to finish your writing by five o’clock today?

—. I’ll be busy with experiments all day.

A. Not a chance

B. Not a little

C. Not to mention it

D. Not a big deal

答案：

(答案→)A. Not a chance

B. Not a little

C. Not to mention it

D. Not a big deal

解析：这是一组对话。上文，你认为你到今天五点能够写完你的著作吗？下文，没有丝毫机会。我一整天都忙着做实验。Not a chance没有丝毫机会Not a little许多Not to mention it更不用说Not a big deal

没什么大不了，根据题意，故选A。