5月23日讯 /生物谷BIOON/ --根据发表在国际学术期刊JAMA Oncology上的一项最新研究，如果能够遵循良好的生活习惯，包括戒烟，避免酗酒，将BMI维持在正常的18.5到27.5之间，并能够每周适度运动至少150分钟或剧烈运动至少75分钟，美国患癌或死于癌症的白种人中很大一部分人或可避免癌症或癌症死亡的发生。在这项研究中，研究人员对两项针对白种人的研究数据进行了分析，检测 健康生活方式 与癌症发生和死亡之间的关系。该研究共包括89571名女性和46399名男性，其中有16531女性和11731名男性完全符合健康生活习惯标准，定义为低风险，其他人定义为高风险。研究人员计算了人群归因风险度，这一概念可解释为如果所有人都按照低风险组的健康生活方式生活，癌症患者不会患癌的比例。研究结果表明，大约20%到40%的癌症病例以及大约一半的癌症死亡事件都可能通过采取低风险组的健康生活方式得到预防。文章作者表示，他们的研究数据仅针对白种人进行估算，不一定适用于其他种族，但是他们选择的这些因素在各个种族中都是已经得到证明的风险因素。这项研究再一次表明生活方式与癌症风险之间存在非常重要的关系，因此研究人员认为一级预防的优先级应当高于癌症控制。遵循健康生活方式是每个人都可以做到的预防癌症发生的经济有效措施。（生物谷）本文系生物谷原创编译整理，欢迎转载！点击。更多资讯请下载.Preventable Incidence and Mortality of Carcinoma Associated With Lifestyle Factors Among White Adults in the United StatesMingyang Song, MD, ScD1,2; Edward Giovannucci, MD, ScDResults A total of 89?571 women and 46?339 men from 2 cohorts were included in the study: 16?531 women and 11?731 men had a healthy lifestyle pattern (low-risk group), and the remaining 73?040 women and 34?608 men made up the high-risk group. Within the 2 cohorts, the PARs for incidence and mortality of total carcinoma were 25% and 48% in women, and 33% and 44% in men, respectively. For individual cancers, the respective PARs in women and men were 82% and 78% for lung, 29% and 20% for colon and rectum, 30% and 29% for pancreas, and 36% and 44% for bladder. Similar estimates were obtained for mortality. The PARs were 4% and 12% for breast cancer incidence and mortality, and 21% for fatal prostate cancer. Substantially higher PARs were obtained when the low-risk group was compared with the US population. For example, the PARs in women and men were 41% and 63% for incidence of total carcinoma, and 60% and 59% for colorectal cancer, respectively.Conclusions and Relevance A substantial cancer burden may be prevented through lifestyle modification. Primary prevention should remain a priority for cancer control.
